unable to open user folder

I am currently unable to open my user folder (named Owner) when I go into Documents and Settings. Either nothing happens at all or the watch glass appears and "not responding" on the top bar. Is there a fix for this? Actually this is the only user folder in use. I cannot get a response for right-clicking either.
Can you do it in safe mode???

if yes then you need to run checkdisk, scan for infections, and/or create a new account and trasfer your data to the new account and delete the old owner account as you might have a corrupted account. see instructions below

How to perform checkdisk

if you do not have Recovery Console installed, then run from the start menu

go to start, run, type in cmd

in cmd type in chkdsk c: /r and press enter

type Y for yes and press enter

type exit and press enter

restart pc, allow checkdisk to finish and run again

this is a lengthy process depending on the size of your harddrive, the percentages will fluctuate, this is normal, you can view report in the event viewer.
go to start>run> and type in eventvwr.msc, click on the applications directory, and in the right hand panel choose winlogon.

and what is your current antivirus??

Download, install, update and do full scan with these free malware detection programs:

Malwarebytes (MBAM): http://www.malwarebytes.org/products/malwarebytes_free
SUPERAntiSpyware: (SAS): http://www.superantispyware.com/

Remove all found, reboot, and run again until scans run clean, these can be removed afterwards if you so choose. Run scans one at a time, please.