Bios disabled serial ports show in device manager

Hi, i need to disable 3 of 4 serial ports and I made this in the bios, so I have only a COM4 enabled into the bios.
Then when i boot after a while like 10 minutes after last shutdown, in device manager, hardware page, i see all the serial ports of my motherboard, then I reboot and now in device manager i see only the com4 serial port!
i would like that on "every" boot only the com4 should be visible, beacuse i need to plug some other devices on usb port that are used as "serial devices" and then they map on other coms 1,2 and 3.

I tried to uninstal serial port from device manager, and also as admin in safe mode, but nothing well, on every boot after a while i get all the serial ports in device manager.

what can i do?
thanks
Giorgio
 
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